Peripheral Nerve Stimulation vs. Spinal Cord Stimulation: Which Is Best for Neuropathic Pain?

June 13, 2025

If you're living with neuropathic pain, you know how frustrating and disruptive it can be. This type of pain originates from damaged or malfunctioning nerves, often leading to burning, tingling, or electric-shock sensations that don’t respond well to traditional treatments. When medications and physical therapy fall short, advanced options like spinal cord stimulation (SCS) and peripheral nerve stimulation (PNS) can offer meaningful relief. But which is right for you?

At Greater Austin Pain Center, our experienced pain doctors help patients choose between these innovative therapies based on their symptoms, goals, and lifestyle. Here’s what you need to know about each option and how to determine the best fit for your condition.

Understanding Neuropathic Pain

Neuropathic pain occurs when the nerves themselves are damaged or misfire, sending faulty pain signals to the brain. This can result from conditions such as diabetes, post-surgical complications, nerve compression, or injuries to the spinal cord. Unlike pain caused by inflammation or tissue damage, neuropathic pain tends to be persistent and harder to manage, often interfering with sleep, work, and daily activities.

What Is Peripheral Nerve Stimulation?

Peripheral nerve stimulation is a minimally invasive treatment that targets specific peripheral nerves, the nerves located outside the brain and spinal cord. A small wire is placed near the problematic nerve and connected to a device that sends low-level electrical pulses. These pulses disrupt the pain signals before they can reach the brain, providing relief right at the source.

This therapy is often ideal for patients dealing with localized pain in areas such as the shoulder, foot, or knee. It’s also frequently used for post-surgical pain or nerve injuries. Because PNS focuses on a single nerve or small group of nerves, it provides precise, targeted relief with minimal impact on other parts of the body.

What Is Spinal Cord Stimulation?

Spinal cord stimulation works on a broader level. Instead of targeting a single nerve, it involves placing electrodes near the spinal cord to influence a wider network of pain pathways. The device emits electrical signals that mask pain signals before they reach the brain, often replacing pain sensations with a gentle tingling or no feeling at all.

SCS is well suited for patients with chronic back pain, leg pain, neck pain, arm pain, pain that radiates from the spine, or pain following unsuccessful back surgery. Because it affects larger regions of the nervous system, it can be a powerful option for patients whose pain is widespread or more complex.

Comparing PNS and SCS

The biggest difference between the two treatments lies in their coverage area. PNS is ideal for localized pain, whereas SCS is better for patients with diffuse or migrating nerve pain. PNS typically requires a simpler procedure and faster recovery, while SCS involves a deeper implant placement but may offer more comprehensive relief. Your overall health, pain location, and previous treatment outcomes will all help determine which option is more suitable.

Which Treatment Is Best for Neuropathic Pain?

If your pain is concentrated in one body part and you’ve responded well to nerve blocks, peripheral nerve stimulation may be your best choice. On the other hand, if your pain radiates down the arms or legs, or you're dealing with failed back surgery syndrome, spinal cord stimulation may offer broader, more effective relief. Both treatments are backed by strong clinical evidence and can significantly improve quality of life when administered by a qualified pain management specialist.

Find Relief with a Back Pain Doctor in Austin

Peripheral nerve stimulation and spinal cord stimulators, both offer powerful relief, but the best choice depends on your unique symptoms and goals. The pain specialists at Greater Austin Pain Center are here to help you make an informed decision. Visit us in Austin, Dripping Springs, San Marcos, Kyle, and throughout the Austin area.

You don’t have to live in constant pain. Contact us to schedule a consultation and find out which nerve stimulation treatment is right for you.

Lunch & Learn With Our Doctors

Curious about interventional pain treatments in Austin, TX? Join our doctors for an in-person lunch and learn session to find out more about these treatments and ask any questions you may have. This event will be 12–1pm, sign up below to receive more details and RSVP.

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Take the First Step to a Pain-free Life

People often experience different levels of pain that need different types of pain care management. We can help you find a customized pain relief regimen that addresses the root issues. Please contact us to schedule an appointment at one of our convenient locations in Austin, Kyle, Dripping Springs, and San Marcos!

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